Crystal structure of mouse protein arginine methyltransferase 7 in complex with SGC8158 chemical probe

Code: 6NPG
Classification: TRANSFERASE
Resolution: 2.94 Å
R-factor: 0.1796
Keywords: PRMT7, SGC8158, chemical probe, Structural Genomics, Structural Genomics Consortium, TRANSFERASE
Deposition Date: 17 January, 2019
Experimental Technique: X-RAY DIFFRACTION
Source Organism:
Expression System:
Biological Assembly: 1

Zinc-Bearing Chains in PDB

1 zinc-bearing chain
Chain A (692 residues; 1 zinc binding site; Spacers: 146, 1, 2 )
mkvfcgranpttgslewleedehydyhqeiarssyadmlhdkdrnikyyqgiraavsrvkdrgqkalvldigtgtgllsmmavtagadfcyaievfkpmaeaavkiverngfsdkikvinkhstevtvgpdgdlpcranilitelfdteligegalpsyehahkhlvqedceavphratvyaqlvesrrmwswnklfpvrvrtslgeqvivppselerCpgapsvcdiqlnqvspadftvlsdvlpmfsvdfskqvsssaachsrqfvplasgqaqvvlswwdiemdpegkikctmapfwaqtdpqelqwrdhwmqcvyflpqeepvvqgsprclvahhddycvwyslqrtspdendsayqvrpvCdCqaHllwnrprfgeindqdrtdhyaqalrtvllpgsvclcvsdgsllsmlahhlgaeqvftvessvasyrlmkrifkvnhledkisvinkrpelltaadlegkkvslllgepffttsllpwhnlyfwyvrtsvdqhlapgavvmpqaaslhavivefrdlwrirspcgdcegfdvhimddmikhsldfresreaephplweypcrslskpqeiltfdfqqpipqqpmqskgtmeltrpgkshgavlwmeyqltpdstistglinpaedkgdccwnphckqavyflsttldlrvplngprsvsyvvefhpltgditmefrladtls

Zinc atoms identified in PDB

1 zinc atom
(A:702)
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