CYCLIC GMP-AMP SYNTHASE in complex with compound 20 inhibitor: 7-hydroxy-N-[(2S)-1-hydroxypropan-2-yl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

Code: 6NFO
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Resolution: 2.93 Å
R-factor: 0.21
Keywords: cGAS, STING, cGAMP, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposition Date: 20 December, 2018
Experimental Technique: X-RAY DIFFRACTION
Source Organism:
Expression System:
Biological Assembly: 1

Zinc-Bearing Chains in PDB

1 zinc-bearing chain
Chain A (362 residues; 1 zinc binding site; Spacers: 5, 0, 6 )
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Zinc atoms identified in PDB

2 zinc atoms
(B:601, A:601)

Zinc atoms not used

B:601: Zinc in asymmetric unit but not biological assembly.
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