Zinc Binding Site: 6NAO-1

PDB

6NAO (Discovery of a high affinity inhibitor of cGAS)

Metals (4 Coordination)

A:601 (ZN)

Liganding Residues (C3H1)

A.390 (HIS)
A.396 (CYS)
A.397 (CYS)
A.404 (CYS)
24 equivalent sites.
4KM5-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
4LEV-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
4LEV-2
residues B.390 (HIS), B.396 (CYS), B.397 (CYS), B.404 (CYS)
4LEW-1
residues B.390 (HIS), B.396 (CYS), B.397 (CYS), B.404 (CYS)
4MKP-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
4O67-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
4O67-2
residues B.390 (HIS), B.396 (CYS), B.397 (CYS), B.404 (CYS)
4O68-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
4O69-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5V8O-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5V8O-2
residues B.390 (HIS), B.396 (CYS), B.397 (CYS), B.404 (CYS)
5VDO-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDP-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDQ-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDR-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDS-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDT-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDU-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDV-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
5VDW-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
6CT9-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
6CTA-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
6NFG-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
6NFO-1
residues A.390 (HIS), A.396 (CYS), A.397 (CYS), A.404 (CYS)
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Chain A Spacers: 5, 0, 6

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PDB Information

Code: 6NAO
Classification: transferase/transferase inhibitor
Resolution: 3.23 Å
R-factor: 0.217
Keywords: cGAS, STING, cGAMP, TRANSFERASE, transferase-transferase inhibitor complex
Deposition Date: 6 December, 2018
Experimental Technique: X-RAY DIFFRACTION
Source Organism:
Expression System:
Biological Assembly: 1